Naloxone is a safe, non-addictive medication that is considered one of the most important heroin overdose prevention tools. It belongs to a class of drugs known as narcotic (opiate) antagonists and works within minutes to block the narcotic’s effects on the brain. Naloxone is used in the treatment of opioid-overdose-induced respiratory depression, in ultra-rapid detoxification, and in combination with buprenorphine for maintenance therapy. Naloxone injection is used for the emergency treatment of opioid overdoses. Naloxone is not a replacement for addiction treatment. It is designed to keep the user alive long enough to get back into treatment.