- ‘Drink responsibly’
- Dalmane
- Dance therapy
- Darvon
- Daytrana
- Debtors Anonymous (DA)
- Delirium tremens
- Delsym
- Delusions
- Demerol
- Denial
- Department of Health and Human Services
- Department of Justice
- Dependence
- Dependent personality disorder
- DepoDur
- Depressants
- Depressed Anonymous
- Depression
- Designer drug
- Desoxyn
- Desoxyn
- Detoxification / detox
- Detoxification process
- Developmental disorders
- Dex-Tuss
- Dexedrine
- Dextroamphetamine
- Dextromethorphan
- Diabulimia
- Diagnosis
- Diagnostic and Statistical Manual of Mental Disorders (DSM)
- Diagnostic orphans
- Dialectical behavioral therapy (DBT)
- Diazepam
- Didrex
- Dilantin
- Dilaudid
- Disease model of addiction
- Disulfiram
- DOC
- Doctor-shopping
- Dolophine
- Domestic violence
- Dopamine
- Dosage
- Drinking (moderate, excessive)
- Drinking while pregnant
- Dronabinol
- Drug
- Drug abuse
- Drug abuse warning network
- Drug abuser
- Drug addiction
- Drug addiction treatment
- Drug and alcohol services information system
- Drug cartels
- Drug classifications
- Drug dependence
- Drug Enforcement Administration
- Drug of choice
- Drug rehab
- Drug replacement therapy
- Drug trafficking
- Drug-seeking behavior
- Drugged driving
- Drunk driving
- Drunkorexia
- Dry drunk
- Dual diagnosis
- Dual Recovery Anonymous (DRA)
- DUI
- Dynamic deconstructive psychotherapy