Mazindol is the generic name for the brand name medications Sanorex and Mazanor. It is a sympathomimetic amine, similar to an amphetamine and is also know as an “anorectic” or an “anorexigenic” drug. This medication is used as a short-term supplement to diet and exercise in the treatment of obesity. Mazindol works by increasing the heart rate and blood pressure while decreasing the appetite. It is generally taken one to three times a day before meals and is in the categories central nervous system agents/CNS stimulants and central nervous system agents/anorexiants. The amount of Mazindol taken by individuals can vary and should be closely monitored by a doctor. Mazindol can be effective in reversing obesity in the right individual, especially when taken under the care of a physician. Some people, however, can have allergic reactions or simply experience negative side effects as a result of taking the drug. Certain serious effects in normal usage can include an irregular heartbeat or very high blood pressure, hallucinations, abnormal behavior or confusion. Less serious effects can also occur and include restlessness, tremors, nervousness, anxiety, headache, dizziness, insomnia, dry mouth, diarrhea, constipation, impotence or changes in sex drive. Mazindol has the potential to work on the brain in much the same way as cocaine and therefore, withdrawal symptoms very closely mimic those of a cocaine addiction and abrupt cessation. Stopping the drug without tapering off use can lead to very uncomfortable withdrawal symptoms and intense cravings.